Revolutionizing Mycotoxin Control with TriSorb αs Multi-Action Strategy

TriSorb-α – Advancing mycotoxin management through multi-action strategy

With the onset of monsoons and increased humidity, the risk of mycotoxin contamination in animal feed escalates significantly, making effective mycotoxin management more critical than ever. Mycotoxins, including Aflatoxins, Ochratoxins, Zearalenone, Fumonisins, and Trichothecenes (DON and T2), represent a significant and persistent challenge to the livestock and poultry industries. These insidious contaminants, often found in raw materials and finished feeds, can lead to reduced feed intake, impaired nutrient utilization, compromised immune function, organ damage, and ultimately, substantial economic losses for producers. Recognizing the urgent need for a robust and reliable defense mechanism, Avitech Nutrition developed TriSorb-α to provide unparalleled protection against a broad spectrum of these harmful compounds.

TriSorb-α’s Multi-Action Mycotoxin Control Strategy: A Holistic Approach

TriSorb-α stands apart from conventional toxin binders through its unique synergistic blend of active components: thermally processed Calcium Montmorillonite, Saccharomyces cerevisiae cell wall components, and Bacillus subtilis. This innovative formulation delivers a powerful multi-action strategy that goes beyond simple adsorption, offering a holistic approach to mycotoxin management:

1. Adsorption: The foundation of TriSorb-α’s efficacy lies in the superior binding capabilities of its primary adsorbents. Thermally processed Calcium Montmorillonite, a highly purified clay mineral, possesses a vast surface area and specific charge characteristics that enable it to effectively bind polar mycotoxins like Aflatoxins. Complementing this, the cell wall polysaccharides (β-glucans and mannanoligosaccharides) derived from Saccharomyces cerevisiae yeast are highly effective in binding a broad range of mycotoxins, including both polar and non-polar types, such as Zearalenone and Ochratoxins. This dual-adsorption mechanism ensures a comprehensive capture of diverse mycotoxins within the gastrointestinal tract, preventing their absorption into the animal’s bloodstream.
2. Biotransformation: A critical differentiator for TriSorb-α is its active biotransformation component. The inclusion of Bacillus subtilis, a beneficial probiotic bacterium, introduces an enzymatic detoxification pathway. Bacillus subtilis secretes specific enzymes that are capable of structurally modifying complex mycotoxins into less toxic or entirely non-toxic metabolites. This enzymatic degradation neutralizes the harmful effects of mycotoxins, offering an additional layer of protection that passive adsorption alone cannot provide. This proactive approach reduces the overall mycotoxin load and minimizes their detrimental impact on animal physiology.
3. Colonization: Beyond enzymatic action, the probiotic Bacillus subtilis in TriSorb-α actively colonizes the animal’s gut. This colonization contributes to a balanced and healthy gut microbiota, which is fundamental to overall animal health and resilience. A robust gut microbiome enhances the animal’s natural detoxification capacity, providing continuous biological protection against ongoing mycotoxin challenges. Furthermore, a balanced gut environment supports optimal nutrient utilization, improves digestive efficiency, and reinforces intestinal barrier integrity, leading to enhanced animal performance and well-being. 

Advanced Mycotoxin Protection: Unlocking Key Benefits

The synergistic action of TriSorb-α’s components translates into a range of significant benefits for feed producers and livestock operations:

• Broad-Spectrum Efficacy: TriSorb-α’s multi-component formulation ensures effective binding and detoxification against a wide array of prevalent mycotoxins, offering robust protection against the complex mycotoxin mixtures often found in contaminated feed.
• pH-Independent Binding: Unlike some binders whose efficacy is compromised by varying pH levels in the digestive tract, TriSorb-α demonstrates consistent high binding efficiency throughout the entire gastrointestinal system, from the acidic stomach to the more alkaline intestines. This ensures continuous and reliable protection.
• Metabolic Detoxification: The unique biotransformation capability provided by Bacillus subtilis actively converts complex and harmful mycotoxins into harmless metabolites, reducing the toxic burden on the animal’s liver and other vital organs.
• Intestinal Health Enhancement: The probiotic colonization by Bacillus subtilis fosters a healthy gut environment, improving nutrient absorption, strengthening the immune system, and further aiding the animal’s natural defense mechanisms against mycotoxin challenges.

Scientific Validation: In-Vitro Studies Confirm TriSorb-α’s Superior Performance

Avitech Nutrition is committed to scientific rigor and has conducted extensive in-vitro studies to validate TriSorb-α’s efficacy:

• Study Conducted at NDDB (National Dairy Development Board) A comprehensive study conducted at the National Dairy Development Board (NDDB) evaluated the net binding efficiency of TriSorb-α against Aflatoxin B1, one of the most potent and widespread mycotoxins. The results unequivocally demonstrated TriSorb-α’s exceptional performance, achieving a remarkable 73% net binding percentage for Aflatoxin B1. This high binding affinity underscores its immediate and powerful protective action.

The National Dairy Development Board (NDDB) evaluated the net binding efficiency of TriSorb-α with Aflatoxin B1 at 98.73%

(B) Studies Conducted at ACNS (Avitech Center for Nutrition Science) Further in-vitro studies at Avitech’s own state-of-the-art Avitech Center for Nutrition Science (ACNS) have provided additional insights into TriSorb-α’s robust performance:

• Study 1: Adsorption Efficacy of TriSorb-α against Aflatoxin B1 at Different pH: This study meticulously evaluated TriSorb-α’s adsorption capabilities across various pH conditions mimicking the different segments of the animal’s digestive tract. The results confirmed its consistent and high binding efficiency for Aflatoxin B1, regardless of the pH environment.

• Study 2: Adsorption Efficacy of TriSorb-α against Zearalenone at Different pH: Similarly, another study at ACNS focused on TriSorb-α’s efficacy against Zearalenone, a non-polar mycotoxin known for its reproductive effects. This research also demonstrated TriSorb-α’s strong and stable adsorption performance across a wide range of pH values, highlighting its broad-spectrum and pH-independent action.

Comprehensive Benefits for Enhanced Animal Performance

The proven efficacy and multi-action approach of TriSorb-α translate into tangible benefits for animal health and production:

• Broad Spectrum Coverage: Protection against a wide range of mycotoxins.
• Optimum Efficiency and Production: Supports improved feed conversion ratios and overall animal productivity.
• High Binding Efficiency: Rapid and effective removal of mycotoxins from the gut.
• No Interaction with Nutrients: Ensures that essential vitamins, minerals, and other nutrients remain available for absorption, preventing nutritional deficiencies.
• Stable in a Wide Range of pH: Consistent performance throughout the digestive tract.
• Affinity Towards Low and High Loads of Mycotoxins: Effective in both preventative and corrective scenarios.
• Healthier Immune System: Reduces immune suppression caused by mycotoxins, leading to more resilient animals.
• Protection of Vital Organs: Minimizes mycotoxin-induced damage to the liver, kidneys, and other critical organs.

Conclusion

TriSorb-α represents a significant advancement in mycotoxin management. One can now confidently enhance feed safety, optimize animal health, and secure economic returns with TriSorb-α. By combining superior adsorption, active biotransformation, and gut colonization, Avitech Nutrition has developed a product that offers unparalleled protection against the complex and evolving threat of mycotoxins.